In plain words
The poet, to the diseases: O diseases grown from strong sins that dim the soul, see: a hard misfortune has come upon you too. Do not come in here, do not come in; it is not easy now, see; do not come in. See, [this self] has become the sacred temple where my master, the Lion Lord, abides. Go and save yourselves before you are put to shame: this town is not what it was before; it is under his guard.