In plain words
The poet, to the diseases: O diseases, afflictions long lodged in me and tormenting me, listen; I will tell you one thing: [this body] has become the sacred temple the Lord who grazed the cattle loves to dwell in; see. Once more I tell you, once and for all, O sins that sank me deep [in the sea of births]: there is no footing for you here, see; be off. This town is not what it was before; it is under his guard.