Verse 43

अविचारणमज्ञानं मौर्ख्यमाहुर्महाधियः ।संसारसंसृतौ सारमन्तःकरणकारणम्

In plain words

Non-inquiry is called ajñāna, is called folly, by the great in understanding. The very substance of the transmigratory round of saṃsāra is that the inner faculty is its cause.