ईशानः प्राणदः प्राणो ज्येष्ठः श्रेष्ठः प्रजापतिः ।
In plain words
The one who rules. The one who gives the breath. The breath itself. The eldest. The finest. The lord of every creature born.
Close to the Sanskrit
The Ruler; the giver of the life-breath; the life-breath; the eldest; the best; the lord of created beings.