Verse 53

यत्नो यत्नेन कर्तव्यो मोक्षार्थं युक्तिपूर्वकम् ।यत्नयुक्तिविहीनस्य गोष्पदं दुस्तरं भवेत्

In plain words

Effort should be made, with effort, for the sake of mokṣa, guided by yukti; for one devoid of effort and yukti, even a cow's footprint becomes hard to cross.